Rezulin Liver Toxicity Symptoms and Diagnosis

Symptoms

Symptoms of liver toxicity due to Rezulin include nausea, vomiting, abdominal pain, fatigue, loss of appetite and the appearance of dark urine. Patients with advanced liver toxicity will exhibit signs of jaundice- a yellowing of skin and eyes.

Diagnosis

Patients that are experiencing any of these symptoms and have used Rezulin should contact their physician immediately to begin treatment.

Patients not experiencing these symptoms but using Rezulin should contact their doctor about switching diabetes medications, as Rezulin is no longer available. Additionally, these patients should undergo testing to determine the extent of damage, if any, to their liver function as a result of the medication.

Damage to liver function could require a period of detoxification, if the damage is mild, or a liver transplant, if the damage is severe.

Find out about treatment options.

Rezulin News Timeline

1997
January - Rezulin is approved by the FDA to treat Type II diabetes.
November - The FDA issues a warning about Rezulin (troglitazone). Recommended prescribing information is changed by the drug's manufacturer; new warning label information is added.
December - Approximately 150 adverse events associated with Rezulin have been reported to the FDA.
1998
June - The FDA and Rezulin manufacturer Parke-Davis agree to again tighten restrictions on the use of Rezulin.
July - Parke-Davis sends a letter to heathcare professionals warning to test for liver abnormalities and updating them on the changes in recommended use.
2001
March - Resulin sales are discontinued.

Contact Us

Questions? Comments? Need Legal help? Contact us today.

Contact Information



Diagnosis

Have you been diagnosed with an rezulin-related disease or injury?:

  • No
  • Yes

If you answered yes, what rezulin-related injury have you been diagnosed with?:

Your Comments:

(Required fields are marked with an *.)

Last Updated: May 11, 2010. 11:08:51 am.